Vittorio Locatelli Selected Research

hexarelin

1/2021	Hexarelin modulates lung mechanics, inflammation, and fibrosis in acute lung injury.
10/2017	JMV2894, a novel growth hormone secretagogue, accelerates body mass recovery in an experimental model of cachexia.
11/2011	Beneficial effects of desacyl-ghrelin, hexarelin and EP-80317 in models of status epilepticus.
9/2009	Desacyl-ghrelin and synthetic GH-secretagogues modulate the production of inflammatory cytokines in mouse microglia cells stimulated by beta-amyloid fibrils.
5/2003	Ghrelin plays a minor role in the physiological control of cardiac function in the rat.

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Vittorio Locatelli Research Topics

Disease

3	Anterior Cruciate Ligament Injuries 01/2018 - 02/2013
3	Wounds and Injuries (Trauma) 01/2017 - 02/2013
2	HIV Infections (HIV Infection) 03/2022 - 01/2019
2	Inflammation (Inflammations) 01/2021 - 02/2013
2	Cachexia 09/2019 - 10/2017
2	Neoplasms (Cancer) 10/2017 - 11/2004
2	Pain (Aches) 01/2017 - 09/2006
2	Seizures (Absence Seizure) 01/2013 - 11/2011
2	Status Epilepticus (Complex Partial Status Epilepticus) 01/2013 - 11/2011
1	Pancreatic Neoplasms (Pancreatic Cancer) 03/2022
1	Melanoma (Melanoma, Malignant) 03/2022
1	Fibrosis (Cirrhosis) 01/2021
1	Acute Lung Injury 01/2021
1	Reperfusion Injury 09/2019
1	Traumatic Brain Injuries (Traumatic Brain Injury) 11/2017
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 11/2017
1	Malnutrition (Nutritional Deficiencies) 10/2017
1	Body Weight (Weight, Body) 10/2017
1	Weight Loss (Weight Reduction) 10/2017
1	Osteoarthritis 01/2016
1	HIV-Associated Lipodystrophy Syndrome 11/2014
1	Bone Resorption 01/2014
1	Osteoporosis 01/2014
1	Rupture 02/2013
1	Dementia (Dementias) 10/2012
1	Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy) 10/2012
1	Obesity 01/2012
1	Epilepsy (Aura) 11/2011
1	Atherosclerotic Plaque (Atheroma) 09/2009
1	Alzheimer Disease (Alzheimer's Disease) 09/2009
1	Edema (Dropsy) 09/2006
1	Hyperalgesia 09/2006
1	Insulin Resistance 02/2005
1	Decapitation 02/2005
1	Ischemia 05/2003
1	Pituitary Dwarfism 02/2003
1	Anorexia 09/2002
1	Hyperplasia 06/2002
1	Carcinoma (Carcinomatosis) 06/2002

Drug/Important Bio-Agent (IBA)

9	GhrelinIBA 09/2019 - 06/2002
5	hexarelinIBA 01/2021 - 05/2003
4	CytokinesIBA 01/2018 - 02/2013
3	Interleukin-6 (Interleukin 6)IBA 01/2018 - 02/2013
3	Interleukin-8 (Interleukin 8)IBA 01/2018 - 02/2013
3	Interleukin-10 (Interleukin 10)IBA 01/2018 - 02/2013
3	SecretagoguesIBA 10/2017 - 05/2003
3	Ghrelin ReceptorsIBA 01/2013 - 09/2006
3	LigandsIBA 11/2011 - 05/2003
2	Insulin (Novolin)FDA Link 03/2022 - 02/2005
2	MicroRNAs (MicroRNA)IBA 03/2022 - 11/2014
2	Cisplatin (Platino)FDA LinkGeneric 09/2019 - 10/2017
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2018 - 02/2013
2	Growth Hormone (Somatotropin)IBA 10/2017 - 01/2013
2	Insulin-Like Growth Factor I (IGF-1)IBA 01/2014 - 02/2005
2	Pilocarpine (Ocusert)FDA LinkGeneric 01/2013 - 11/2011
1	Nerve Growth Factors (Neurotrophins)IBA 03/2022
1	JMV2894IBA 10/2017
1	NeuropeptidesIBA 01/2017
1	A 7 (A-7)IBA 02/2013
1	Diazepam (Valium)FDA LinkGeneric 01/2013
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2013
1	macimorelinIBA 01/2013
1	Neuroprotective AgentsIBA 01/2013
1	Amyloid (Amyloid Fibrils)IBA 10/2012
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2012
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2012
1	Kainic Acid (Kainate)IBA 11/2011
1	des-n-octanoyl ghrelinIBA 11/2011
1	Amyloid beta-PeptidesIBA 09/2009
1	EP80317IBA 09/2009
1	Opioid Analgesics (Opioids)IBA 09/2006
1	P-30 composite resin (P 30)IBA 09/2006
1	CarrageenanIBA 09/2006
1	BIM 23627IBA 02/2005
1	Messenger RNA (mRNA)IBA 02/2005
1	Hormones (Hormone)IBA 02/2005
1	Therapeutic UsesIBA 09/2002
1	Amino Acids FDA Link 06/2002

Therapy/Procedure

2	Therapeutics 01/2019 - 11/2017
1	Drug Therapy (Chemotherapy) 10/2017